PubChem is a freely accessible database created by the National Institutes of Health (NIH) to provide information about small organic molecules. It is designed for use as a research tool and as a starting point that may lead to the development of new medications. The database connects chemical information with biomedical research and clinical information, organizing facts in numerous databases into a unified whole. PubChem is a critical component of NIH’s Molecular Libraries Initiative, which in turn is a key element of the NIH strategic “roadmap” to speed new medical treatments and improve healthcare.
PubChem also includes the PubChem BioAssay Database, containing bioactivity screens of chemical substances described in PubChem Substance. It provides searchable descriptions of each bioassay, including descriptions of the conditions and readouts specific to that screening procedure.